Pharmacy Research
Through pharmacy research, we’re studying best practices when it comes to using medication. Every day, with every study, we work to answer questions like:
- What’s the best medication or combination to treat this condition?
- What should the pharmacist’s role be in a specific patient care scenario?
- How can the pharmacy department better partner with other healthcare members to offer patients the highest level of care?
- What regulations or protocols need to exist around the administration of this drug?
Cone Health has a long-standing history of pharmacy involvement with research, and in 2018 developed an official committee to help give this important arm of research even more focus and dedicated resources. The committee coordinates pharmacy department-led research projects, facilitates research training for pharmacy investigators, reviews research proposals, supports success of each project by providing feedback and guidance and monitors compliance with institutional review board.
Pharmacy Resident Research Projects
2024-2025
- Evaluating the Effectiveness and Safety of a Pharmacist Driven Electrolyte Replacement Protocol
- Incidence of AKI Before and After Implementation of Pharmacy-Driven Acyclovir Protocol
- Evaluating Anti-Hypertensive Compliance Amongst African American Patients through In-patient and Outpatient Pharmacist Collaboration
- Incidence of Adverse Effects Associated with High Dose Intrapartum Vancomycin Administration for GBS Prophylaxis
- Use of Prophylactic Amiodarone for the Prevention of Atrial Fibrillation After Coronary Artery Bypass Graft Surgery
- Antidote Assessment in a Community Health System
- Evaluating IV Iron Discordance Among Patients within Cone Health Outpatient Infusion Centers
- Achievement of Functional Cure of Hepatitis B Infection Among Patients Co-Infected with HIV on Tenofovir Based Antiretroviral Therapy
- Evaluation of the Impact of Urinalysis Reflex to Culture Criteria Implementation
- Evaluation of a Pharmacist Driven ICU Bowel Regimen
- Evaluation of Ambulatory care Pharmacist Interventions in Patients with T2DM with Medicaid Managed Care Contracts
- Optimization of Pharmacist Interventions for a Health Equity Initiative to Improve Hypertension Control in African Americans
- Evaluating the Impact of a Community Pharmacist-Led Blood Pressure Screening Service to Improve Hypertension Control
- Assessment of Impella Purge Bicarbonate Solutions to UFH Solutions
- Impact of Phenobarbital on ICU Length of Stay in Alcohol Withdrawal Syndrome
- Implementation of a Sublocade Long-Acting Injectable Clinic
- Evaluation of Universal Admission HIV Screening at a Community Hospital
- Evaluation of Topical Diclofenac Use on the Incidence and Severity of Hand Food Syndrome in Patients with Breast and GI Malignancies Taking Capecitabine
- Intravenous Push Keppra in Status Epilepticus in Pediatric Patients
2023-2024
- Impact of Pharmacist Targeted Interventions in the Management and Prevention of CKD in patients with Hypertension
- Pharmacist-Led Health Equity Initiative to Improve Hypertension Control in African American Patients
- Impact of Community Pharmacist Transitions of Care Post-Discharge Calls for High Risk Medications
- Levetiracetam for neonatal seizures
- Evaluation of Early Initiation of Basal Insulin in Pediatric DKA
- Impact of BioFire ® FilmArray ® Meningitis/Encephalitis (ME) Panel on Anti-infective Use
- Evaluation of Antibiotic Administration Surrounding Interventional Radiology Procedures
- Use of IV Cetirizine in Place of IV Diphenhydramine for the Prevention of Hypersensitivity Reactions
- Optimization of Daratumumab Based Treatment Plans
- Direct Oral Anticoagulant Use After Transcatheter Aortic Valve Replacement for Atrial Fibrillation Patients
- Retrospective Evaluation of 4-Factor Prothrombin Complex Concentrate versus Andexanet alfa for DOAC Reversal
- Impact of a Pharmacist Led Intervention for Conversion from Intravenous Heparin to Oral Anticoagulation in Patients with New Onset Nonvalvular Atrial Fibrillation
- The Impact of Pharmacist-Driven Insulin Management in the Intensive Care Unit
- Evaluation of the safety and tolerability of a treprostinil DPI compared to nebulized solution in patients with pulmonary arterial hypertension
- Pre- and Post-Implementation of a Specialty Pharmacy Dashboard to Assess Prescription Capture to Optimize Performance
- Alteplase vs Tenecteplase in Acute Ischemic Stroke at a Community Medical Center
- Evaluation of a nurse & pharmacist driven phenobarbital protocol for alcohol withdrawal syndromes
- Midodrine for Vasopressor Liberation In Patients with Septic Shock
- Development of an Outpatient Infusion Strategy for a Community Hospital and Health System
2022-2023
- Assessing length of antibiotic therapy pre- and post-implication of early stewardship intervention for uncomplicated intestinal perforations with or without abscess
- Time on vasopressor therapies as affected by a standardized vasopressor weaning protocol
- Optimizing steroid use through paclitaxel order-sets in the outpatient infusion center
- Comparison of outcomes with titratable versus fixed-dose heparin use in continuous renal replacement therapy
- A multidisciplinary team approach to oncology drug utilization management at a community cancer center
- Impact of a pharmacist-driven discharge transitions of care process in patients hospitalized with HF or ACS
- Impact of pharmacist-driven driven discharge medication order review
- Impact of pharmacist-led smoking cessation service in pulmonary clinic
- Impact of pharmacist targeted interventions in the management of hypertriglyceridemia in patients with DM2 at high risk for cardiovascular disease
- Development of an outpatient infusion strategy at a community hospital
- Productivity model assessing IV robots in hazardous drug preparation
- The identification and implementation of targeted efforts to increase the value of oncology medication therapy
- Implementing an automated dispensing cabinet override monitoring dashboard at a regional health system
- Impact of a pharmacist-led weight management service in a cardiology clinic
- Evaluation of low dose 1 mg NovoSeven post-CABG
- An assessment of fixed rate obinutuzumab infusion in follicular lymphoma and chronic lymphocytic leukemia
- Infectious diseases and palliative care collaboration to optimize antibiotic use at the end of life
- Evaluation of pharmacy integration into a pediatric emergency department
2021-2022
- Evaluating the 30-day incidence of venous thromboembolism (VTE) following diagnosis of coronavirus disease 2019 (COVID-19) among hospitalized patients
- Evaluating the impact of a pharmacy technician float pool within a regional health system
- Assessment of surgical prophylaxis choice in patients undergoing joint replacement or spine surgery
- Impact of pharmacist targeted interventions in the management of dyslipidemia in patients with coronary artery disease
- Evaluation of emergency department culture report interventions among clinical pharmacy specialists
- Optimizing the continuation of home medications on admission using pharmacist review
- Lactated ringers versus normal saline in diabetic ketoacidosis fluid resuscitation
- Implementation analysis of a standardized medication therapy management program in the transition of care pharmacy
- Evaluating the safety and efficacy of standardized dose ranges for vasopressors in extremes of body weight: a retrospective study
- Increasing dual antiplatelet therapy prescribing in patients with ACS post-CABG surgery
- Pharmacist optimization of lipid therapy in patients with peripheral vascular disease
- Impact of pharmacist targeted interventions in prevention of atherosclerotic cardiovascular disease in patients with diabetes mellitus
Pharmacy Student Research Projects
2024-2025
- ACE inhibitors or ARBs post TAVR
- Impact of student telephonic outreach on control of BP
- Evaluation of patient characteristics of those with multiple HEDIS quality measure fails
- Medication Use Evaluation of Droxidopa
- Nephrotic Syndrome and VTE
- Evaluation of 24 hour rule out for neonatal early onset sepsis
- Tobacco/Nicotine use disorder evaluation of interventions including use of guideline directed medications
- Medication Use Evaluation of Droperidol in Cone Health Emergency Departments
2023-2024
- Evaluation of Pharmacist Impact on Hypertension Control in a Family Medicine Practice: A health disparity quality improvement interdisciplinary intervention
- Evaluation of Student Pharmacist Engagement on Hypertension Control in a Population Health Model
- Evaluating IV Iron Discordance Among Patients Within Cone Health Outpatient Infusion Centers
- Vancomycin Area Under the Curve (AUC) Target Attainment in Obese Patients
- Evaluating Real-World Use of Rivaroxaban 10 mg Daily for Venous Thromboembolism Prophylaxis in Acute Care Patients
- Savings generated from an investigational drug service within a community hospital setting
2022-2023
- Evaluation of ASA use in CV primary prevention patients 60-69 years of age
- Retrospective evaluation of fixed-dose 4F-PCC protocol for VKA reversal
- An analysis of infectious diseases intervention on outcomes in gram-negative bacteremia
- Outcomes of daily versus twice daily intrapleural administration of alteplase and dornase alfa
- MUE of ADE with SGLT2
- Evaluation of pharmacy gentamicin dosing algorithm in neonates
2021-2022
- Educational intervention with pre-post survey of knowledge/confidence prescribing methadone for hospice patients
- DOAC evaluation
- GLP-1a/SGLT2i in ASCVD patients in internal medicine
- Standardized neonatal admission and sepsis order sets in predicting length of antibiotic therapy
- Hypertonic saline peripheral administration
- Lactated ringers versus normal saline initial sepsis resuscitation
- Evaluation of an interprofessional geriatrics assessment clinic
- LEAN evaluation of time to dispense in NICU
- Piqray evaluation: Baseline BG/HbA1c, time on target dose, antihyperglycemics, supportive therapy medications
- Cephalosporins in HD patients
- Nerlynx usage, antidiarrheal Rxs and directions/actual usage, length on therapy, starting dose, time to target dose, develop protocol
- Improving specialty pharmacy adherence through automated, digital regill assessments
- GLP-1a in end-stage renal disease
- Evaluation of lipid management in patients with diabetes
- Interdisciplinary tobaccos cessation during COVID-19 pandemic in a family medicine clinic
Do you have a pharmacy research project you’re looking to submit for presentation or publication? Here are a few resources:
